Human Primary Diabetic Artery Smooth Muscle Cells
BVXDS002
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IncludedProduct Details
Size
1ml
Product Code
BVXDS002
Quick Specifications
- Product Type: Human Type II Diabetes Endothelial Cells
- Viability: >95% viable (Trypan Blue exclusion)
- Storage: Store in liquid nitrogen vapor phase (-196°C) for long-term. Ship on dry ice (-80°C).
- Shelf Life: Very stable in the Liquid Nitrogen Vapor Phase
- Catalog: BVXDS002
- Growth: Primary cells capable of multiple passages when using recommended medium and proper handling
Human Primary Diabetic Artery Smooth Muscle Cells
Product Description
Human Primary Smooth Muscle Cells from arteries of individuals with diabetes are specialized cells that play a crucial role in the vascular system. These cells are characterized by their response to hyperglycemic conditions, which can lead to changes in their proliferation, migration, and contractility. In the context of diabetes, these smooth muscle cells may exhibit altered signaling pathways, contributing to vascular complications such as atherosclerosis and hypertension. Guarantee expansion for a minimum of 2-5 population doublings. IMPORTANT: Quality warranty requires use of Bioverax media. Biohazardous material despite negative pathogen testing. Quality claims must be reported within 1 month.
Key Features & Benefits
Catalog Number: BVXDS002 Product Format: Frozen Vial Cell Number: > 5x10[5] cells/vial Passage:1(P1) Storage: Liquid Nitrogen, Vapor Phase Intended Use: Research use only (RUO) Characterization Markers Characterized by positive expression of smooth muscle cell-specific alpha-actin .
Quick Facts
Product Type
Human Type II Diabetes Endothelial Cells
Viability
>95% viable (Trypan Blue exclusion)
Storage
Store in liquid nitrogen vapor phase (-196°C) for long-term. Ship on dry ice (-80°C).
Shelf Life
Very stable in the Liquid Nitrogen Vapor Phase
Applications
Technical Specifications
| Product Type | Human Type II Diabetes Endothelial Cells |
|---|---|
| Viability | >95% viable (Trypan Blue exclusion) |
| Proliferative Capability | Primary cells capable of multiple passages when using recommended medium and proper handling |
| Storage Conditions | Store in liquid nitrogen vapor phase (-196°C) for long-term. Ship on dry ice (-80°C). |
| Shelf Life | Very stable in the Liquid Nitrogen Vapor Phase |
| Product Code | BVXDS002 |
| Size/Format | 1ml |
| Category | Primary Cells |
Primary Applications
Applications & Use Cases
Primary Applications
Proliferation and Migration: Diabetic VSMCs often exhibit increased proliferation and migration in response to high glucose or insulin
Suitable for proliferation and migration: diabetic vsmcs often exhibit increased proliferation and migration in response to high glucose or insulin studies and research applications
contributing to neointimal hyperplasia. Advanced Glycation End-products (AGEs): Studying how AGEs (which accumulate in diabetes) interact with their receptor (RAGE) on VSMCs to cause inflammation. Oxidative Stress: Measuring reactive oxygen species (ROS). VSMCs from diabetic donors usually have impaired antioxidant defenses. Contractility: Examining the switch from a 'contractile' (healthy
Suitable for contributing to neointimal hyperplasia. advanced glycation end-products (ages): studying how ages (which accumulate in diabetes) interact with their receptor (rage) on vsmcs to cause inflammation. oxidative stress: measuring reactive oxygen species (ros). vsmcs from diabetic donors usually have impaired antioxidant defenses. contractility: examining the switch from a 'contractile' (healthy studies and research applications
quiescent) phenotype to a 'synthetic' (pathological
Suitable for quiescent) phenotype to a 'synthetic' (pathological studies and research applications
proliferative) phenotype. Epigenetics: Investigating how high glucose has permanently altered gene expression (e.g.
Suitable for proliferative) phenotype. epigenetics: investigating how high glucose has permanently altered gene expression (e.g. studies and research applications
via histone modifications) even when cells are removed from the body.
Suitable for via histone modifications) even when cells are removed from the body. studies and research applications
Research Use Cases
In Vitro Studies
Cell culture and screening applications
Molecular Biology
Gene expression & signaling studies
Drug Discovery
Screening & validation studies
Technical Support & Documentation
Technical Support
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