Human Primary Diabetic Pulmonary Vein Smooth Muscle Cells

BVXDS010

$900.00
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Human Primary Diabetic Pulmonary Vein Smooth Muscle Cells
Primary Cells 1ml In Stock

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$900.00
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$900.00
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Size

1ml

Product Code

BVXDS010

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Quick Specifications
  • Product Type: Human Type II Diabetes Endothelial Cells
  • Viability: >95% viable (Trypan Blue exclusion)
  • Storage: Store in liquid nitrogen vapor phase (-196°C) for long-term. Ship on dry ice (-80°C).
  • Shelf Life: Very stable in the Liquid Nitrogen Vapor Phase
  • Catalog: BVXDS010
  • Growth: Primary cells capable of multiple passages when using recommended medium and proper handling

Human Primary Diabetic Pulmonary Vein Smooth Muscle Cells

Product Description

Primary Smooth Muscle Cells derived from the Pulmonary Veins of human patients diagnosed with diabetes mellitus, characterized by specific alterations in their cellular function and behavior due to the disease. These cells are used for research into the effects of diabetes on vascular health and may play a role in understanding complications related to pulmonary circulation. Guarantee expansion for a minimum of 2-5 population doublings. IMPORTANT: Quality warranty requires use of Bioverax media. Biohazardous material despite negative pathogen testing. Quality claims must be reported within 1 month.

Key Features & Benefits

Catalog Number: BVXDS010 Product Format: Frozen Vial Cell Number: > 5x10[5] cells/vial Passage:1(P1) Storage: Liquid Nitrogen, Vapor Phase Intended Use: Research use only (RUO) Marker Expression: Positive for Alpha Smooth Muscle Actin . Positive for Desmin. Positive for Calponin and SM22 (specific SMC markers). Negative for von Willebrand Factor (vWF) / CD31 (to confirm absence of endothelial cells). Negative for Cytokeratin (to confirm absence of epithelial cells).

Quick Facts
Product Type

Human Type II Diabetes Endothelial Cells

Viability

>95% viable (Trypan Blue exclusion)

Storage

Store in liquid nitrogen vapor phase (-196°C) for long-term. Ship on dry ice (-80°C).

Shelf Life

Very stable in the Liquid Nitrogen Vapor Phase

Applications
Diabetic Vascular Remodeling: Investigating how high glucose alters the growth and death rates of venous smooth muscle. Signal Transduction: Studying pathways like PKC (Protein Kinase C) MAPK/ERK or advanced glycation end-products (AGEs) and their receptor (RAGE) in a diabetic context. Pharmacological Testing: Screening new drugs aimed at preventing vascular stiffness or treating pulmonary hypertension specifically in diabetic patients. Inflammation: Examining the interaction between hyperglycemia and inflammatory cytokine production in the vessel wall.

Technical Specifications

Product Type Human Type II Diabetes Endothelial Cells
Viability >95% viable (Trypan Blue exclusion)
Proliferative Capability Primary cells capable of multiple passages when using recommended medium and proper handling
Storage Conditions Store in liquid nitrogen vapor phase (-196°C) for long-term. Ship on dry ice (-80°C).
Shelf Life Very stable in the Liquid Nitrogen Vapor Phase
Product Code BVXDS010
Size/Format 1ml
Category Primary Cells
Primary Applications
Diabetic Vascular Remodeling: Investigating how high glucose alters the growth and death rates of venous smooth muscle. Signal Transduction: Studying pathways like PKC (Protein Kinase C) MAPK/ERK or advanced glycation end-products (AGEs) and their receptor (RAGE) in a diabetic context. Pharmacological Testing: Screening new drugs aimed at preventing vascular stiffness or treating pulmonary hypertension specifically in diabetic patients. Inflammation: Examining the interaction between hyperglycemia and inflammatory cytokine production in the vessel wall.

Applications & Use Cases

Primary Applications
Diabetic Vascular Remodeling: Investigating how high glucose alters the growth and death rates of venous smooth muscle. Signal Transduction: Studying pathways like PKC (Protein Kinase C)

Suitable for diabetic vascular remodeling: investigating how high glucose alters the growth and death rates of venous smooth muscle. signal transduction: studying pathways like pkc (protein kinase c) studies and research applications

MAPK/ERK

Suitable for mapk/erk studies and research applications

or advanced glycation end-products (AGEs) and their receptor (RAGE) in a diabetic context. Pharmacological Testing: Screening new drugs aimed at preventing vascular stiffness or treating pulmonary hypertension specifically in diabetic patients. Inflammation: Examining the interaction between hyperglycemia and inflammatory cytokine production in the vessel wall.

Suitable for or advanced glycation end-products (ages) and their receptor (rage) in a diabetic context. pharmacological testing: screening new drugs aimed at preventing vascular stiffness or treating pulmonary hypertension specifically in diabetic patients. inflammation: examining the interaction between hyperglycemia and inflammatory cytokine production in the vessel wall. studies and research applications

Research Use Cases
In Vitro Studies

Cell culture and screening applications

Molecular Biology

Gene expression & signaling studies

Drug Discovery

Screening & validation studies

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