Human Primary Diabetic Skeletal Muscle Cells

BVXDS011

$900.00
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Human Primary Diabetic Skeletal Muscle Cells
Primary Cells 1ml In Stock

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$900.00
Quantity: 1
$900.00
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Size

1ml

Product Code

BVXDS011

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Quick Specifications
  • Product Type: Human Type II Diabetes Endothelial Cells
  • Viability: >95% viable (Trypan Blue exclusion)
  • Storage: Store in liquid nitrogen vapor phase (-196°C) for long-term. Ship on dry ice (-80°C).
  • Shelf Life: Very stable in the Liquid Nitrogen Vapor Phase
  • Catalog: BVXDS011
  • Growth: Primary cells capable of multiple passages when using recommended medium and proper handling

Human Primary Diabetic Skeletal Muscle Cells

Product Description

Human Primary Skeletal Muscle Cells derived from individuals with diabetes. These specialized cells are significant for studying the effects of diabetes on muscle metabolism, insulin sensitivity, and overall cellular function. Guarantee expansion for a minimum of 2-5 population doubles. IMPORTANT: Quality warranty requires use of Bioverax media. Biohazardous material despite negative pathogen testing. Quality claims must be reported within 1 month.

Key Features & Benefits

Catalog Number: BVXDS011 Product Format: Frozen Vial Cell Number: > 5x10[5] cells/vial Passage:1(P1) Storage: Liquid Nitrogen, Vapor Phase Intended Use: Research use only (RUO) Characterization Markers Characterized by positive expression of smooth muscle cell-specific alpha-actin )

Quick Facts
Product Type

Human Type II Diabetes Endothelial Cells

Viability

>95% viable (Trypan Blue exclusion)

Storage

Store in liquid nitrogen vapor phase (-196°C) for long-term. Ship on dry ice (-80°C).

Shelf Life

Very stable in the Liquid Nitrogen Vapor Phase

Applications
Drug Discovery: Screening novel anti-diabetic compounds (e.g. investigating if a drug can resensitize these cells to insulin independent of the pancreas). Mechanistic Studies: Using siRNA or CRISPR-Cas9 to knock down specific genes (e.g. GLUT4 +2 more

Technical Specifications

Product Type Human Type II Diabetes Endothelial Cells
Viability >95% viable (Trypan Blue exclusion)
Proliferative Capability Primary cells capable of multiple passages when using recommended medium and proper handling
Storage Conditions Store in liquid nitrogen vapor phase (-196°C) for long-term. Ship on dry ice (-80°C).
Shelf Life Very stable in the Liquid Nitrogen Vapor Phase
Product Code BVXDS011
Size/Format 1ml
Category Primary Cells
Primary Applications
Drug Discovery: Screening novel anti-diabetic compounds (e.g. investigating if a drug can resensitize these cells to insulin independent of the pancreas). Mechanistic Studies: Using siRNA or CRISPR-Cas9 to knock down specific genes (e.g. GLUT4 *PGC-1?*) to understand their role in the maintenance of the diabetic phenotype. Exercise Mimetics: Studying how electrical pulse stimulation (EPS) or pharmacological agents affect contraction-mediated glucose uptake in a 'diabetic' environment. Inflammation: Investigating the role of pro-inflammatory cytokines (IL-6 TNF-?) secreted by diabetic muscle.

Applications & Use Cases

Primary Applications
Drug Discovery: Screening novel anti-diabetic compounds (e.g.

Suitable for drug discovery: screening novel anti-diabetic compounds (e.g. studies and research applications

investigating if a drug can resensitize these cells to insulin independent of the pancreas). Mechanistic Studies: Using siRNA or CRISPR-Cas9 to knock down specific genes (e.g.

Suitable for investigating if a drug can resensitize these cells to insulin independent of the pancreas). mechanistic studies: using sirna or crispr-cas9 to knock down specific genes (e.g. studies and research applications

GLUT4

Suitable for glut4 studies and research applications

*PGC-1?*) to understand their role in the maintenance of the diabetic phenotype. Exercise Mimetics: Studying how electrical pulse stimulation (EPS) or pharmacological agents affect contraction-mediated glucose uptake in a 'diabetic' environment. Inflammation: Investigating the role of pro-inflammatory cytokines (IL-6

Suitable for *pgc-1?*) to understand their role in the maintenance of the diabetic phenotype. exercise mimetics: studying how electrical pulse stimulation (eps) or pharmacological agents affect contraction-mediated glucose uptake in a 'diabetic' environment. inflammation: investigating the role of pro-inflammatory cytokines (il-6 studies and research applications

TNF-?) secreted by diabetic muscle.

Suitable for tnf-?) secreted by diabetic muscle. studies and research applications

Research Use Cases
In Vitro Studies

Cell culture and screening applications

Molecular Biology

Gene expression & signaling studies

Drug Discovery

Screening & validation studies

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