Human Primary Diabetic Vein Smooth Muscle Cells

BVXDS013

$900.00
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Human Primary Diabetic Vein Smooth Muscle Cells
Primary Cells 1ml In Stock

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$900.00
Quantity: 1
$900.00
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Size

1ml

Product Code

BVXDS013

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Quick Specifications
  • Product Type: Human Type II Diabetes Endothelial Cells
  • Viability: >95% viable (Trypan Blue exclusion)
  • Storage: Store in liquid nitrogen vapor phase (-196°C) for long-term. Ship on dry ice (-80°C).
  • Shelf Life: Very stable in the Liquid Nitrogen Vapor Phase
  • Catalog: BVXDS013
  • Growth: Primary cells capable of multiple passages when using recommended medium and proper handling

Human Primary Diabetic Vein Smooth Muscle Cells

Product Description

Human Primary Diabetic Vein Smooth Muscle Cells are a specialized type of cell line derived from human veins affected by diabetes. These cells exhibit unique characteristics that reflect the physiological and pathological conditions associated with diabetes, particularly in relation to vascular health. They are essential for studying the effects of diabetes on vascular smooth muscle function, signaling pathways, and potential therapeutic interventions aimed at improving cardiovascular outcomes in diabetic patients. Guarantee expansion for a minimum of 2-5 population doublings. IMPORTANT: Quality warranty requires use of Bioverax media. Biohazardous material despite negative pathogen testing. Quality claims must be reported within 1 month.

Key Features & Benefits

Catalog Number: BVXDS013 Product Format: Frozen Vial Cell Number: > 5x10[5] cells/vial Passage:1(P1) Storage: Liquid Nitrogen, Vapor Phase Intended Use: Research use only (RUO) Characterization Markers Characterized by positive expression of smooth muscle cell-specific alpha-actin.

Quick Facts
Product Type

Human Type II Diabetes Endothelial Cells

Viability

>95% viable (Trypan Blue exclusion)

Storage

Store in liquid nitrogen vapor phase (-196°C) for long-term. Ship on dry ice (-80°C).

Shelf Life

Very stable in the Liquid Nitrogen Vapor Phase

Applications
Restenosis and Vein Graft Failure: Diabetic patients have significantly higher rates of vein graft occlusion after bypass surgery. Researchers use these cells to test drugs (e.g. mTOR inhibitors anti-proliferatives) that might prevent the excessive smooth muscle cell proliferation that closes off the graft. Diabetic Vasculopathy: Understanding why diabetic patients suffer from accelerated atherosclerosis and peripheral artery disease (PAD) involving the venous system. Wound Healing: Venous insufficiency is a major cause of diabetic foot ulcers. Studying the contractility and migration of these cells helps understand why wound contraction fails in diabetic patients. Drug Screening: Pharmaceutical companies use these primary cells to test the vascular toxicity or efficacy of new antidiabetic drugs +1 more

Technical Specifications

Product Type Human Type II Diabetes Endothelial Cells
Viability >95% viable (Trypan Blue exclusion)
Proliferative Capability Primary cells capable of multiple passages when using recommended medium and proper handling
Storage Conditions Store in liquid nitrogen vapor phase (-196°C) for long-term. Ship on dry ice (-80°C).
Shelf Life Very stable in the Liquid Nitrogen Vapor Phase
Product Code BVXDS013
Size/Format 1ml
Category Primary Cells
Primary Applications
Restenosis and Vein Graft Failure: Diabetic patients have significantly higher rates of vein graft occlusion after bypass surgery. Researchers use these cells to test drugs (e.g. mTOR inhibitors anti-proliferatives) that might prevent the excessive smooth muscle cell proliferation that closes off the graft. Diabetic Vasculopathy: Understanding why diabetic patients suffer from accelerated atherosclerosis and peripheral artery disease (PAD) involving the venous system. Wound Healing: Venous insufficiency is a major cause of diabetic foot ulcers. Studying the contractility and migration of these cells helps understand why wound contraction fails in diabetic patients. Drug Screening: Pharmaceutical companies use these primary cells to test the vascular toxicity or efficacy of new antidiabetic drugs ensuring that therapies intended to lower glucose do not inadvertently cause vascular smooth muscle proliferation.

Applications & Use Cases

Primary Applications
Restenosis and Vein Graft Failure: Diabetic patients have significantly higher rates of vein graft occlusion after bypass surgery. Researchers use these cells to test drugs (e.g.

Suitable for restenosis and vein graft failure: diabetic patients have significantly higher rates of vein graft occlusion after bypass surgery. researchers use these cells to test drugs (e.g. studies and research applications

mTOR inhibitors

Suitable for mtor inhibitors studies and research applications

anti-proliferatives) that might prevent the excessive smooth muscle cell proliferation that closes off the graft. Diabetic Vasculopathy: Understanding why diabetic patients suffer from accelerated atherosclerosis and peripheral artery disease (PAD) involving the venous system. Wound Healing: Venous insufficiency is a major cause of diabetic foot ulcers. Studying the contractility and migration of these cells helps understand why wound contraction fails in diabetic patients. Drug Screening: Pharmaceutical companies use these primary cells to test the vascular toxicity or efficacy of new antidiabetic drugs

Suitable for anti-proliferatives) that might prevent the excessive smooth muscle cell proliferation that closes off the graft. diabetic vasculopathy: understanding why diabetic patients suffer from accelerated atherosclerosis and peripheral artery disease (pad) involving the venous system. wound healing: venous insufficiency is a major cause of diabetic foot ulcers. studying the contractility and migration of these cells helps understand why wound contraction fails in diabetic patients. drug screening: pharmaceutical companies use these primary cells to test the vascular toxicity or efficacy of new antidiabetic drugs studies and research applications

ensuring that therapies intended to lower glucose do not inadvertently cause vascular smooth muscle proliferation.

Suitable for ensuring that therapies intended to lower glucose do not inadvertently cause vascular smooth muscle proliferation. studies and research applications

Research Use Cases
In Vitro Studies

Cell culture and screening applications

Molecular Biology

Gene expression & signaling studies

Drug Discovery

Screening & validation studies

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